The current estimate about rare diseases or about those called orphan because they are not interesting for the pharmaceutical industry since the cases are too few is of about 6,500, most likely an underestimate.
As a rule, when the origin of the pathology faced can’t be found, it is tagged as idiopathic or cryptogenic, two adjectives meaning “I did not understand.” But a culprit must be found and, so, genetics or psychosomatics, two hypotheses that are often hard to deny because stringent evidence is not required, become easy ways out.
It is a fact that in recent years doctors see with an unusual frequency pathologies that were so far extremely rare or unknown at all, or syndromes, i.e. collections of symptoms, so apparently unconnected as to look utterly unlikely. That is what happens, for instance, more than once to veterans repatriated from territories where a war is being or has been fought.
An epidemiologically striking increase is what is occurring for allergies and for the numerous autoimmune diseases which, simplifying the concept, make the subjects grow allergic to themselves. In either cases, the real causes are not always identified. In that great class of pathologies, Multiple Chemical Sensitivity (MCS) can be inserted, a condition that is often, crudely and without the least trace of scientific rationale, treated with psychotropic drugs, a therapy useful only to the doctor who, administering them, makes the patients less annoying to himself. It is true that the subjects suffering from MCS can show manifestations of a disturbed psychology, but those who know that kind of patients are aware that that is not the cause but one of the consequences of a disease that disrupts the patient’s life under many points of views, including social relations.
And even cancer, the pathology that is characterizing the topicality, has origins to say the least controversial.
We are beginning only recently to compare this multiplication of diseases whose origin does not appear in the classical texts with the growing, equally considerable, phenomenon of air, water and food pollution, and it is impossible not to notice how the two curves proceed more or less in parallel.
The discovery of micro- and nanosized dust pollutants in pathological tissues, in semen and blood of those who suffer from some of those diseases should begin at least to arouse some curiosity.
With their electron-microscopy techniques and their great database in excess of 2,000 human cases studied directly, Nanodiagnostics detect the presence of solid, inorganic particles in the patient’s biological samples, thus giving them the possibility to move away from the polluting source that caused and sustains the disease.